Cancer Biology & Therapy

SEP 8, 2026 · JOURNAL ARTICLE

Thioredoxin reductase-1 facilitates cellular plasticity and stemness mediated by TGF-β1 in non-small cell lung cancer.

Cancer Biology & Therapy

Mechanistic study in cell lines and a mouse model identifying a pathway without clinical endpoint data or direct evidence of therapeutic benefit in humans.

AUG 11, 2026 · JOURNAL ARTICLE

The molecular mechanisms of platelets in tumor invasion and metastasis: a controversial role.

Cancer Biology & Therapy

This is a narrative review synthesizing mechanistic evidence on platelet-tumor interactions without reporting primary experimental or clinical data, clinical endpoints, or quantified effect sizes.

JUL 28, 2026 · JOURNAL ARTICLE

DNA polymerase theta (Polθ): a novel candidate for targeted cancer therapy.

Cancer Biology & Therapy

A narrative review synthesizing current knowledge on Polθ biology, therapeutic rationale, and drug development status—informative for researchers and clinicians but not reporting original empirical data or trial outcomes.

JUL 28, 2026 · JOURNAL ARTICLE

Molecular interplay of insulin resistance and cancer: advances in monoclonal antibody therapeutics.

Cancer Biology & Therapy

This is a narrative review proposing mechanistic connections between insulin resistance and cancer, with speculative discussion of monoclonal antibody therapeutics, but no primary experimental or clinical data to support efficacy claims.

JUL 27, 2026 · JOURNAL ARTICLE

Stress-specific 14-3-3-client modules in digestive cancers: an evidence-graded review of adaptive survival and therapy resistance.

Cancer Biology & Therapy

Narrative review synthesizing mechanistic evidence from functional studies in digestive cancers; no new primary data, clinical validation limited, and therapeutic translation not yet established.

JUL 26, 2026 · JOURNAL ARTICLE

Targeting molecular and genetic pathways driving tumorigenesis for precision therapy in colorectal cancer.

Cancer Biology & Therapy

This is a narrative review synthesizing existing knowledge about molecular pathways in colorectal cancer and therapeutic strategies, without presenting new primary data, clinical trials, or original findings to evaluate.

JUL 20, 2026 · JOURNAL ARTICLE

Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin.

Cancer Biology & Therapy

In vitro study demonstrates reversal of cisplatin resistance in one cell line via ALDH and ABCC2 inhibition, requiring validation in additional models and clinical testing.

JUL 14, 2026 · JOURNAL ARTICLE

xinguangA preliminary characterization of PI4K/PIPK alterations across solid tumors: an exploratory framework for prognostic and therapeutic stratification.

Cancer Biology & Therapy

Exploratory retrospective analysis identifying genomic alteration patterns and associations, requiring prospective validation before clinical implementation.