Bioactive Materials

OCT 13, 2026 · JOURNAL ARTICLE

Microenvironmental barriers to healing in osteoradionecrosis and opportunities for regenerative intervention

Bioactive Materials

Osteoradionecrosis (ORN) is a debilitating sequela of radiotherapy (RT) for head and neck cancer (HNC), characterized by persistent bone exposure or radiographic non-viability and

SEP 23, 2026 · JOURNAL ARTICLE

Calcium dysregulation in synergy with sonodynamic therapy via medroxyprogesterone-targeted and ROS-responsive nanoparticles for endometrial cancer

Bioactive Materials

Effective therapies that enable precise drug delivery and integrated monitoring are urgently needed for fertility-sparing management of endometrial cancer (EC). Although calcium ch

SEP 22, 2026 · JOURNAL ARTICLE

Ultrasound-responsive nanotherapy promotes axonal regeneration after SCI via reactivating CREB/miR-129-5p signaling.

Bioactive Materials

Spinal cord injury (SCI) remains a devastating neurological disorder with few effective therapeutic interventions due to the poor intrinsic regenerative capacity of adult central n

SEP 17, 2026 · JOURNAL ARTICLE

Dynamic coordination engineering of gallium biomaterials: A biological accessibility framework for therapeutic biofunction

Bioactive Materials

Gallium (Ga)-based biomaterials have emerged as versatile therapeutic platforms owing to the iron-mimicking properties and broad biological activities of gallium. Coordination engi

SEP 16, 2026 · JOURNAL ARTICLE

A bladder microenvironment-adaptive ceria nanozyme hydrogel enables urea-responsive intravesical chemo-immunotherapy

Bioactive Materials

Bladder cancer intravesical therapy remains limited by rapid urinary washout, insufficient penetration across the bladder mucosal barrier, and an immunosuppressive tumor microenvir

SEP 15, 2026 · JOURNAL ARTICLE

Dismantling the eDNA-mediated H2S barrier with biohybrids against refractory biofilm infections.

Bioactive Materials

The spatiotemporal distribution of gaseous mediators is critical for maintaining physiological functions. Biofilms both contain gas-producing bacteria and possess complex architect

SEP 12, 2026 · JOURNAL ARTICLE

Programmable 4D printing of sustainable multifunctional photoresins with tissue-matched mechanics for interfacial tissue regeneration.

Bioactive Materials

The integrative regeneration of articular cartilage and subchondral bone remains a major clinical challenge due to the difficulties of mimicking the spatial and compositional compl

SEP 8, 2026 · JOURNAL ARTICLE

From pathogenic to reparative: Context-Dependent function of extracellular vesicles in osteoarthritis.

Bioactive Materials

Osteoarthritis (OA) is a whole-joint disease characterized by progressive structural degeneration and chronic low-grade inflammation affecting the cartilage, synovium, subchondral