Bioactive Materials

AUG 22, 2026 · JOURNAL ARTICLE

Harnessing necroptosis via RIPK1 degradation to potentiate radio-immunotherapy in cervical cancer.

Bioactive Materials

Preclinical mechanistic study in cell and animal models demonstrating a potential strategy; no clinical trial data, human efficacy evidence, or comparison to standard care reported.

AUG 12, 2026 · JOURNAL ARTICLE

Cerium molybdate-doped polyaniline nanoplatform for GSH-depletion-enhanced chemodynamic/NIR-II photothermal synergistic therapy via ferroptosis and immune activation

Bioactive Materials

This is a preclinical mechanistic study of a novel nanoparticle in an experimental system; it demonstrates proof-of-concept but lacks clinical translation, human data, or controlled comparison to standard therapy.

AUG 12, 2026 · JOURNAL ARTICLE

Magnetically responsive electrospun fibers as programmable bioactive scaffolds: From formulation design to magnetically triggered therapy and regeneration

Bioactive Materials

This is a narrative review synthesizing preclinical and mechanistic evidence on an emerging material platform; it raises questions about clinical potential rather than answering them with clinical trial data.

AUG 11, 2026 · JOURNAL ARTICLE

Preclinical evaluation of PSMA-targeted ultrasound contrast agents in an orthotopic model of prostate cancer in rabbits.

Bioactive Materials

First-in-vivo preclinical study of a novel PSMA-targeted nanobubble contrast agent in an orthotopic rabbit model, demonstrating proof-of-concept with exploratory endpoints constrained by small cohort size and non-specific histologic validation.

AUG 5, 2026 · JOURNAL ARTICLE

Biomaterial-based extracellular vesicle delivery systems for wound healing: From fabrication to applications.

Bioactive Materials

This is a comprehensive review article synthesizing current knowledge on biomaterial-based extracellular vesicle delivery systems for wound healing, presenting fabrication strategies, release mechanisms, and applications rather than reporting primary experimental evidence.

AUG 5, 2026 · JOURNAL ARTICLE

Biomimetic stress granules replenish lysosomal repair to reinstate macrophage immunometabolic antibacterial programs.

Bioactive Materials

This is a mechanistic study using engineered nanomaterials and cell models to propose a novel repair pathway; it raises questions about stress granule exhaustion in infection rather than answering them with clinical or in vivo efficacy data.

AUG 4, 2026 · JOURNAL ARTICLE

Loss of EGFR activity in skeletal stem/progenitor cells is associated with impaired fracture healing in aged mice.

Bioactive Materials

Sound mechanistic study in aged mice using genetic models and a novel hydrogel intervention showing accelerated fracture healing, but limited to preclinical animal work without human efficacy data or clinical trial evidence.

AUG 4, 2026 · JOURNAL ARTICLE

A hierarchical, pH-responsive nanocomposite hydrogel platform for synergistic microenvironment reprogramming and attenuation of inflammatory periodontal bone loss.

Bioactive Materials

Early-stage in vivo validation of a novel nanocomposite hydrogel in a murine periodontitis model with no clinical data, comparative controls, or quantified efficacy metrics reported.