Abstract Background PSMA PET/CT plays an important role in biochemically recurrent prostate cancer (BCR-PCa). In general, PET/CT is performed as a limited or true whole-body examin
Abstract Background This study aimed to evaluate the associations of mammographic and ultrasonographic features with histopathological characteristics and immunohistochemistry-defi
Abstract Background Accurate preoperative assessment of HER2 status is critical for guiding targeted therapy, but conventional biopsy-based methods are invasive and limited by tumo
Abstract Background Molecular profiling tests currently relies significantly on genomics or transcriptomics analysis, leading a prolonged turnaround time and higher costs procedure
Retrospective, single-centre study with modest sample size and surrogate endpoint (mutation status prediction); requires prospective multicentre validation before clinical use, as stated by the authors.
Post hoc analysis of a phase II trial with small sample (n=29) and surrogate/exploratory endpoints; findings are hypothesis-generating and require validation in larger populations.
A well-designed secondary analysis of prospectively acquired imaging data with independent expert assessment and rigorous statistical methods, but limited to a single-centre cohort of 35 patients evaluating a surrogate imaging quality endpoint rather than clinical outcomes.