Adipocyte

OCT 14, 2026 · JOURNAL ARTICLE

The pro-obesity role of G3BP1 through altering adipogenic differentiation in mice via the PI3K/AKT pathway

Adipocyte

As a growing but non-infectious epidemic, obesity is a common cause of several comorbidities. GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is a central regulator

OCT 9, 2026 · JOURNAL ARTICLE

Comparative analysis of select 3D human mesenchymal stromal cell-derived spheroid models for adipogenic differentiation.

Adipocyte

In vitro modelling of adipose tissue (AT) commonly employs 2D systems, which do not fully capture the complexity of AT, lacking cell-cell interactions and extracellular matrix (ECM

SEP 27, 2026 · JOURNAL ARTICLE

The extracellular matrix protein SNED1 affects self-renewal, proliferation and adipogenic differentiation of human adipose stem/progenitor cells.

Adipocyte

The fate of adipose stem/progenitor cells (ASCs) is influenced by the extracellular matrix (ECM). However, the interaction between ASCs and components of the ECM in human white adi

AUG 24, 2026 · JOURNAL ARTICLE

Assessment of the safety and efficacy of sodium pentaborate pentahydrate in individuals with overweight and obesity: a randomized, double-blind, placebo-controlled, phase 1/2 dose-finding trial.

Adipocyte

Phase 1/2 dose-finding trial with modest sample size (116 completers) and short 12-week duration showing exploratory efficacy signals without major safety concerns, but requiring confirmation in phase 3 trials before clinical application.

AUG 20, 2026 · JOURNAL ARTICLE

Lipedema and obesity: biological interactions, diagnostic challenges, and principles of interdisciplinary management - a narrative review.

Adipocyte

A narrative review synthesizing clinical and biological evidence on lipedema and obesity interaction, intended to support clinical reasoning and interdisciplinary management rather than to estimate treatment effects or replace formal guidelines.

AUG 18, 2026 · JOURNAL ARTICLE

Autofluorescence profiles define depot-specific adipocyte phenotypes in perivascular and non-perivascular adipose tissue.

Adipocyte

This is a small, single-centre, proof-of-concept study in rats using a novel autofluorescence approach to characterize adipocyte phenotypes, lacking clinical outcome data and human validation.

JUL 26, 2026 · JOURNAL ARTICLE

Depot-specific differences in visceral and subcutaneous adipose tissue from patients with obesity.

Adipocyte

Small paired-sample observational study characterizing metabolic differences between adipose depots in obesity; provides mechanistic insights but lacks a comparator group and is underpowered for clinical translation.