Drug or technology

Drug Therapy

2 developments in the corpus

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AUG 24, 2026 · JOURNAL ARTICLE

Assessment of the safety and efficacy of sodium pentaborate pentahydrate in individuals with overweight and obesity: a randomized, double-blind, placebo-controlled, phase 1/2 dose-finding trial.

Adipocyte

Phase 1/2 dose-finding trial with modest sample size (116 completers) and short 12-week duration showing exploratory efficacy signals without major safety concerns, but requiring confirmation in phase 3 trials before clinical application.

PreliminaryFateme Tahmasbi Drug Therapy Obesity

Reported

Sample size (completers)116

Sample size (randomized)177

Body weight change, 1,000 mg group−3.1 kg

MAY 23, 2026 · JOURNAL ARTICLE

Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction.

Den Open

Retrospective cohort shows stenting strategy impacts time to reintervention and survival in chemotherapy-treated malignant hilar obstruction, with one independent factor identified in multivariable analysis.

PromisingDrug Therapy Kazuma Daiku Katsuhiko Sato

Reported

Sample size81

Median follow-up425 days

Median survival479 days