Def-EI. Condition with an energy-restriction energy deficit / Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary r / Pediatric Obesity · Interventional Study

Appetite Response to Exercise- Versus Mixed (Exercise + Dietary Restriction)-Induced Energy Deficit in Adolescents With Obesity

ClinicalTrials.gov · August 7, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a completed but unresulted registry record for a small three-arm trial comparing appetite and energy intake response to exercise-only, mixed exercise plus dietary restriction, and control conditions in adolescents with obesity. No outcome data are reported in this registry record, precluding any inference about efficacy or clinical benefit.

What was studied

Interventional, Single Group, Open label, Treatment purpose. Pediatric Obesity; age from 12 Years; to 17 Years; accepts healthy volunteers. Intervention: Obese adolescents. Compared with: Control condition without exercise / rest condition (CON). n = 17. 1 site: France.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a completed registry record with no posted results; the planned primary outcome is appetite and energy intake response across three intervention arms in adolescents with obesity.

Study design

As stated by the source record.

MethodsPrimary outcome measure: Change from different intervention of energy intake measured during an ad libitum buffet meal (in kcal). (assessed at day 1, day 8, day 15)

DesignInterventional, Single Group, Open label, Treatment purpose

PopulationPediatric Obesity; age from 12 Years; to 17 Years; accepts healthy volunteers

Sample size17

InterventionObese adolescents

ComparatorControl condition without exercise / rest condition (CON)

Setting1 site: France

Reported figures

Quoted from the source exactly as published.

Planned enrollment17

Primary outcome measureChange from different intervention of energy intake measured during an ad libitum buffet meal (in kcal)

Measurement timepointsday 1, day 8, day 15

Caveats

This registry record reports no results; outcome data are not posted and cannot be assessed.
No details on randomization, blinding, or allocation concealment provided.
Study methods (e.g., exercise dose, dietary restriction magnitude, duration between interventions) not described in registry record.
No sample size justification or power analysis reported.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

moderate

Three-arm behavioral intervention trial with control; design stated but no blinding or randomization detail provided.

Directness

strong

Directly measures ad libitum energy intake and appetite in target population with obesity.

Consistency

insufficient

Single-arm registry record; no comparative results or prior literature cited.

Risk of bias

insufficient

Registry record does not describe blinding, allocation concealment, or outcome assessment methods.

Sample adequacy

limited

Actual enrollment 17 participants across three arms; small sample size.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT04734639). This is a study registration, not published results. Lead sponsor: University Hospital, Clermont-Ferrand. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 17 participants (ACTUAL). Conditions: Pediatric Obesity. Interventions: BEHAVIORAL: CON . control condition without exercise / rest condition; BEHAVIORAL: Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary restriction.; BEHAVIORAL: Def-EI. Condition with an energy-restriction energy deficit. Primary outcome measures: Change from different intervention of energy intake measured during an ad libitum buffet meal (in kcal). , day 1, day 8, day 15. Brief summary: The aim of the present study is to compare the effect of iso-energetic energy deficits induced by energy restriction alone or exercise + dietary restriction (Mixed deficit) on energy intake and appetite feelings in adolescents with obesity.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Def-EI. Condition with an energy-restriction energy deficitUniversity Hospital, Clermont-FerrandNCT04734639Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary rPediatric ObesityCON . control condition without exercise / rest condition