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Cardiac Valve Diseases and Treatments · Journal article
Circulation Cardiovascular Interventions · September 11, 2026
A consensus or society position rather than new primary data.
This is a narrative review and expert guidance statement synthesizing evidence on transcatheter edge-to-edge repair in older adults with mitral and tricuspid regurgitation. The authors report that randomized trials and registries support durable reduction in regurgitation, improved function, and lower heart failure hospitalization rates across age groups, but highlight critical evidence gaps in frailty characterization, long-term functional outcomes, and age-specific risk stratification tools, recommending integration of geriatric assessment and multidisciplinary care pathways.
Journal article. Older adults with mitral regurgitation or tricuspid regurgitation ineligible for surgery. Intervention: Transcatheter edge-to-edge repair.
Randomized trials and contemporary registries demonstrate durable reduction in regurgitation, improved functional status, and lower heart failure hospitalizations with transcatheter edge-to-edge repair across age groups Integration of Comprehensive Geriatric Assessment, Mini Nutritional Assessment-Short Form, Katz Index, Kansas City Cardiomyopathy Questionnaire, and cognitive screening enables individualized risk stratification Periprocedural strategies including structured rehabilitation, early mobilization, delirium prevention, and caregiver engagement enhance functional recovery
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
Clinicians caring for older adults with regurgitant valve disease should consider transcatheter edge-to-edge repair as a safe alternative and integrate geriatric assessment tools to optimize procedural outcomes and postprocedural recovery. Future management requires standardized frailty and cognitive assessment in clinical trials and development of integrated multidisciplinary care pathways aligned with patient-centered functional and quality-of-life goals.
Expert consensus and narrative review synthesizing evidence on transcatheter edge-to-edge repair in older adults, identifying clinical gaps and recommending integrated geriatric assessment strategies, but not reporting original trial data or meta-analysis.
As stated by the source record.
Clinicians caring for older adults with regurgitant valve disease should consider transcatheter edge-to-edge repair as a safe alternative and integrate geriatric assessment tools to optimize procedural outcomes and postprocedural recovery. Future management requires standardized frailty and cognitive assessment in clinical trials and development of integrated multidisciplinary care pathways aligned with patient-centered functional and quality-of-life goals.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no reported figures. That is a gap in the analysis, not a judgement about the study.
The older adult population is expanding rapidly. Parallel to this expansion, cardiologists care for a larger population of patients with clinically significant mitral regurgitation and tricuspid regurgitation who are ineligible for surgical repair due to frailty, multimorbidity, and coexisting geriatric conditions. Transcatheter edge-to-edge repair has emerged as a safe and effective alternative, with randomized trials and contemporary registries demonstrating durable reduction in regurgitation, improved functional status, and lower heart failure hospitalizations across age groups. Integration of geriatric cardiology tools to address frailty, cognition, delirium risk, nutrition, polypharmacy, and social support is critical to optimize procedural outcomes. Tools including the Comprehensive Geriatric Assessment, Mini Nutritional Assessment-Short Form, Katz Index of Independence in Activities of Daily Living, Kansas City Cardiomyopathy Questionnaire, and cognitive screening instruments enable individualized risk stratification and care planning. Periprocedural and postprocedural strategies, including structured rehabilitation, early mobilization, delirium prevention, and caregiver engagement, further enhance functional recovery. Despite favorable procedural outcomes, significant gaps remain in the care for older adults, including the inconsistent characterization of frailty and cognitive status in clinical trials, which limits evidence to guide selection, limited transcatheter edge-to-edge repair-specific tools to assess age-associated risks, and scarcity of long-term data on functional independence and quality-of-life end points. Future research should prioritize patient-centered outcomes and develop integrated, multidisciplinary care pathways that align procedural success with meaningful life expectancy and functional longevity in older adults.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.