Hemodynamic Monitoring and Therapy · Journal article
World Journal of Gastrointestinal Surgery · September 4, 2026
Encouraging direction, but not yet definitive.
This retrospective cohort study of 130 gastric cancer surgery patients found that stroke volume variation-guided GDFT compared to conventional fluid therapy was associated with faster return of gastrointestinal function, reduced nursing workload, shorter length of stay, and lower postoperative gastrointestinal dysfunction rates. The magnitude of effects is clinically plausible but retrospective design precludes causal attribution; confirmation in a randomized controlled trial is needed before practice change.
Retrospective cohort study. Patients undergoing elective gastric cancer surgery under general anesthesia between August 2023 and October 2025.. Intervention: Goal-directed fluid therapy (GDFT) guided by stroke volume variation under anesthesia. Compared with: Conventional fluid therapy (CFT). n = 130.
Time to first flatus: 2.3 ± 0.6 days (GDFT) vs 3.1 ± 0.8 days (CFT), P < 0.001 Time to first bowel movement: 3.2 ± 0.7 days (GDFT) vs 4.3 ± 1.1 days (CFT), P < 0.001 Nursing Activities Score: 42.5 ± 6.8 (GDFT) vs 51.3 ± 8.2 (CFT), P < 0.001
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
If validated by randomized controlled trial, stroke volume variation-guided GDFT could become standard perioperative fluid management for gastric cancer surgery, reducing postoperative recovery time and care burden. Retrospective design and single-centre setting limit current applicability to clinical practice.
A single-centre retrospective cohort comparing GDFT to conventional fluid therapy shows consistent benefits across gastrointestinal recovery and nursing workload endpoints, but retrospective design and lack of randomization limit definitive causal inference.
As stated by the source record.
Quoted from the source exactly as published.
If validated by randomized controlled trial, stroke volume variation-guided GDFT could become standard perioperative fluid management for gastric cancer surgery, reducing postoperative recovery time and care burden. Retrospective design and single-centre setting limit current applicability to clinical practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
BACKGROUND Goal-directed fluid therapy (GDFT) has emerged as a pivotal strategy for perioperative optimization.However, its effects on postoperative gastrointestinal recovery and nursing workload in patients undergoing gastric cancer surgery remain insufficiently understood.AIM To evaluate the impact of stroke volume variation-guided GDFT on postoperative gastrointestinal function and nursing workload in patients undergoing gastric cancer surgery.METHODS This article included 130 patients who underwent elective gastric cancer surgery under general anesthesia between August 2023 and October 2025.Patients were divided into GDFT and conventional fluid therapy (CFT) groups, with 65 patients in each group.The primary outcomes were time to first flatus, time to first bowel movement, and the Nursing Activities Score.Secondary outcomes included length of stay, postoperative complications, and inflammatory markers. RESULTSCompared with the CFT group, the GDFT group experienced significantly faster gastrointestinal recovery, with a shorter time to first flatus (2.3 ± 0.6 days vs 3.1 ± 0.8 days) and first bowel movement (3.2 ± 0.7 days vs 4.3 ± 1.1 days) (both P < 0.001).The overall nursing workload was significantly lower in the GDFT group than in the CFT group (42.5 ± 6.8 vs 51.3 ± 8.2; P < 0.001).The GDFT group also had a shorter length of stay (8.4 ± 1.9 days vs 10.7 ± 2.6 days; P < 0.001) and a lower incidence of postoperative gastrointestinal dysfunction (6.2% vs 21.5%, P = 0.012). / 29 CONCLUSIONStroke volume variation-guided GDFT was associated with faster gastrointestinal recovery, a lower nursing workload, and improved perioperative outcomes in this retrospective cohort of patients undergoing gastric cancer surgery.
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