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Lung Cancer Research Studies / Chemotherapy-induced Cardiotoxicity and Mitigation · Journal article
Journal of Asian Pacific Society of Cardiology · August 8, 2026
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This is a descriptive survey documenting current diagnostic and management practices for cancer therapy-related cardiac dysfunction among cardiologists in Indonesia. Although 94% report awareness of European Society of Cardiology guidelines, substantial heterogeneity in clinical practice is observed, particularly in surveillance scheduling, use of advanced imaging modalities, and comprehensive heart failure therapy adoption. The study does not measure patient outcomes or compare effectiveness of different approaches.
Cross-sectional electronic survey. Cardiologists involved in cancer therapy-related cardiac dysfunction care at 65 medical centres across Indonesia.. n = 65. Indonesia; 65 medical centres.
94% of respondents reported referring to European Society of Cardiology guidelines for CTRCD management Echocardiography follow-up schedules were determined at oncologist's discretion in 50.8% of cases rather than by standardised protocols Global longitudinal strain was reported as not routinely used by 53.8% of respondents
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This survey documents implementation gaps in CTRCD care in a low- to middle-income setting but does not provide evidence about which practice patterns improve patient outcomes. Clinicians should recognise the variability as a call for standardisation rather than as evidence that any particular approach is superior.
A descriptive cross-sectional survey of self-reported practice patterns with no control group, outcome data, or clinical endpoints; documents variation in care delivery but does not measure efficacy or clinical impact.
As stated by the source record.
Quoted from the source exactly as published.
This survey documents implementation gaps in CTRCD care in a low- to middle-income setting but does not provide evidence about which practice patterns improve patient outcomes. Clinicians should recognise the variability as a call for standardisation rather than as evidence that any particular approach is superior.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Background: Cancer therapy-related cardiac dysfunction (CTRCD) has emerged as a major complication of modern cancer therapy, particularly as cancer survival continues to improve. Although international guidelines provide standardised recommendations for CTRCD surveillance and management, real-world implementation remains highly variable, especially in low- and middle-income settings. Key diagnostic modalities include left ventricular ejection fraction and global longitudinal strain, ideally integrated within a multidisciplinary cardio-oncology framework. Aim: To characterise real-world practice patterns and inter-centre variation in CTRCD screening, monitoring and management across participating centres in Indonesia. Methods: A cross-sectional electronic survey was conducted between July and August 2025 among cardiologists involved in CTRCD care. Participants were recruited using cluster-based sampling from 65 medical centres across Indonesia. Results: A total of 65 responses were analysed. Although most respondents (94%) reported referring to European Society of Cardiology guidelines, substantial variation in clinical practice was observed. Echocardiography follow-up schedules were frequently determined at the oncologist’s discretion (50.8%) rather than by standardised protocols. Usage of global longitudinal strain and cardiac biomarkers remained limited, with 53.8 and 64.6% of respondents reporting no routine use, respectively. Comprehensive guideline-based heart failure therapy, ‘four pillars’, was implemented by 47.7% of respondents. Post-treatment surveillance strategies also differed considerably across institutions. Conclusion: Despite high guideline awareness, CTRCD diagnosis and management in Indonesia remain heterogeneous, with limited adoption of advanced surveillance strategies. These findings highlight the urgent need for standardised national monitoring pathways, strengthened multidisciplinary collaboration, and targeted capacity-building programmes to improve early detection and long-term cardiovascular outcomes among cancer survivors.
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