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Metronome / Alzheimer Disease (AD) / Mild Cognitive Impairment (MCI) · Interventional Study
ClinicalTrials.gov · August 7, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a clinical trial registry record for a planned interventional study evaluating rhythmic auditory stimulation (metronome-guided walking) on brain connectivity and gait in Alzheimer's disease and mild cognitive impairment. No results have been posted in this registry record, so no evidence of efficacy or safety can be assessed.
Interventional, Single Group, Open label, Other purpose. Alzheimer Disease (AD), Mild Cognitive Impairment (MCI); age from 50 Years; to 90 Years; accepts healthy volunteers. Intervention: Effects of RAS on gait quality on brain activity in individ…. n = 40. 1 site: United States.
This is a clinical trial registry record for a planned interventional study evaluating rhythmic auditory stimulation (metronome-guided walking) on brain connectivity and gait in Alzheimer's disease and mild cognitive impairment. No results have been posted in this registry record, so no evidence of efficacy or safety can be assessed.
This is a registry record with no results posted; no efficacy or safety data are available.
The source did not state who this applies to in practice.
This is a study registration with no results posted; it describes planned enrollment and outcome measures for an interventional study of rhythmic auditory stimulation in Alzheimer's disease that is still recruiting.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07659964). This is a study registration, not published results. Lead sponsor: Boston University Charles River Campus. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 40 participants (ESTIMATED). Conditions: Alzheimer Disease (AD), Mild Cognitive Impairment (MCI). Interventions: OTHER: Metronome. Primary outcome measures: Functional brain network connectivity , within session: baseline (no RAS) and RAS-assisted walking; Stride time variability , within session: baseline (no RAS) and RAS-assisted walking; Gait speed , within session: baseline (no RAS) and RAS-assisted walking. Brief summary: Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a nearly threefold higher rate of falls compared to neurotypical older adults. There is an urgent need for fall prevention interventions tailored to the unique deficits of individuals with AD. Converging evidence suggests that interventions aiming to reduce fall risk in AD should target both gait and cognition. Rhythmic music interventions, such as Rhythmic Auditory Stimulation (RAS) can harness global brain activation and auditory-motor entrainment to facilitate high-intensity exercise to alleviate AD-related neurocognitive and gait dysfunction. This study aims to assess the neural correlates of gait dysfunction in people with AD, evaluate if baseline neurocognitive impairment is predictive of the effects of RAS, and evaluate RAS benefits for individuals with AD.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.