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Dementia Disorders / Mild Cognitive Impairment (MCI) · Observational Study
ClinicalTrials.gov · September 10, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned observational registry study comparing plasma GFAP, structural MRI volumes, and EEG band power across normal aging, mild cognitive impairment, and dementia groups in an Egyptian population. No results are yet available in this registry record; the study is still in pre-recruitment phase and describes only planned outcome measures at a single baseline assessment.
Observational. Dementia Disorders, Mild Cognitive Impairment (MCI); age from 50 Years; accepts healthy volunteers. Intervention: Dementia; Mild Cognitive impairment; control. n = 75. Egypt (Assiut University, lead sponsor)..
This is a planned observational registry study comparing plasma GFAP, structural MRI volumes, and EEG band power across normal aging, mild cognitive impairment, and dementia groups in an Egyptian population. No results are yet available in this registry record; the study is still in pre-recruitment phase and describes only planned outcome measures at a single baseline assessment.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is a registry record for an observational study not yet recruiting; no results are posted, and the design involves cross-sectional biomarker collection at a single time point without intervention or outcome comparison.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07812480). This is a study registration, not published results. Lead sponsor: Assiut University. Recruitment status: NOT_YET_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 75 participants (ESTIMATED). Conditions: Dementia Disorders, Mild Cognitive Impairment (MCI). Primary outcome measures: Plasma Concentration of Glial Fibrillary Acidic Protein (GFAP)main outcome , Baseline (single time point); Hippocampal Volume on MRI, Whole-Brain Volume on MRI,Ventricular Volume on MRI , Baseline (single time point); EEG Band Power Alpha , beta , delta , theta , Baseline (single time point). Brief summary: Memory problems can range from normal aging to mild cognitive impairment (MCI) to dementia. This study looks at three ways of measuring what is happening in the brain at each of these stages: a blood test (GFAP), a brain MRI scan, and a brain wave test (EEG). The goal is to see whether combining these three tests can help doctors tell the difference between normal aging, MCI, and dementia more accurately, and whether this approach works well in an Egyptian population, including all common causes of dementia (not only Alzheimer's disease). Adults aged 50 to 85 will be placed into one of three groups: those with normal memory, those with mild memory problems (MCI), and those with dementia. Everyone will have a memory and thinking assessment, a blood draw, a brain MRI, and a brain wave (EEG) recording. No new medication or treatment is given as part of this study; it involves only assessment and testing. The information gathered may help doctors diagnose memory problems earlier and more accurately in the future.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.