Osteoarthritis, Knee / Positive Minds, Strong Joints · Interventional Study

Positive Minds Strong Joints for Knee Osteoarthritis

ClinicalTrials.gov · August 11, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a single-arm feasibility study of a combined physical and mental health intervention for knee osteoarthritis in Black adults, with enrollment completed but clinical results not yet reported in this registry record. The study measured recruitment, retention, attendance, and satisfaction rather than clinical outcomes; no efficacy or safety data are available.

What was studied

Interventional, Single Group, Open label, Treatment purpose. Osteoarthritis, Knee; age from 50 Years. Intervention: Positive Minds Strong Joints. n = 39. 1 site: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a feasibility study with enrollment complete but results not yet reported; primary outcomes are recruitment, retention, and satisfaction metrics rather than clinical efficacy.

Study design

As stated by the source record.

MethodsPrimary outcome measures: Recruitment Rate (assessed at Throughout the recruitment process); Retention (assessed at From the start of the study to end of the 10 week intervention); Attendance (assessed at During 10 weeks intervention period); Satisfaction with treatment (assessed at week 10 and week 22); Participant Feedback (assessed at week 10 and week 22)

DesignInterventional, Single Group, Open label, Treatment purpose

PopulationOsteoarthritis, Knee; age from 50 Years

Sample size39

InterventionPositive Minds Strong Joints

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Planned enrollment39

Intervention duration10 weeks

Follow-up period22 weeks

Primary outcome: Recruitment rateThroughout the recruitment process

Primary outcome: RetentionFrom the start of the study to end of the 10 week intervention

Primary outcome: AttendanceDuring 10 weeks intervention period

Primary outcome: Satisfaction with treatmentweek 10 and week 22

Caveats

Results not yet reported in this registry record; study status is active but not recruiting.
No comparator group; cannot assess efficacy or superiority relative to standard care.
Primary outcomes are feasibility metrics (recruitment, retention, satisfaction), not clinical endpoints such as pain, function, or mobility.
Sample size (n=39) is typical for feasibility studies but insufficient to draw clinical conclusions.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

moderate

Single-arm interventional feasibility study with defined enrollment and follow-up.

Directness

moderate

Targets stated population (Black adults with knee OA) but primary outcomes are operational, not clinical.

Consistency

insufficient

No comparator group; consistency cannot be assessed from registry record.

Risk of bias

insufficient

Registry record does not describe blinding, allocation, or other bias mitigation methods.

Sample adequacy

limited

39 participants enrolled; appropriate for feasibility study but underpowered for efficacy claims.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT06493903). This is a study registration, not published results. Lead sponsor: Boston University Charles River Campus. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 39 participants (ACTUAL). Conditions: Osteoarthritis, Knee. Interventions: BEHAVIORAL: Positive Minds, Strong Joints. Primary outcome measures: Recruitment Rate , Throughout the recruitment process; Retention , From the start of the study to end of the 10 week intervention; Attendance , During 10 weeks intervention period; Satisfaction with treatment , week 10 and week 22; Participant Feedback , week 10 and week 22. Brief summary: The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Osteoarthritis, KneeNCT06493903Positive Minds, Strong JointsBoston University Charles River Campus