Institution

The Cleveland Clinic

3 developments in the corpus

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AUG 18, 2026 · INTERVENTIONAL STUDY

Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty

ClinicalTrials.gov

This is a planned clinical trial registration with no results reported; enrollment has not yet begun, making it an early-stage study that cannot yet provide evidence on effectiveness.

PreliminaryNCT07770633 Prevena Obesity

Reported

Planned sample size300

Primary outcome measureSurgical complications (superficial infecti…

Follow-up duration90 days post-op

AUG 12, 2026 · INTERVENTIONAL STUDY

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

ClinicalTrials.gov

Active trial with no results yet reported; early-phase intervention study in cognitively normal e4 carriers examining surrogate endpoints of cognition and brain volume.

PreliminaryExercise Intervention Normal Cognition NCT04748861

Reported

Enrollment150

Primary outcome measure 1Rey Auditory Verbal Learning Test Total Rec…

Primary outcome measure 2Total Hippocampal Volume (THV) at 18 months

AUG 3, 2026 · OBSERVATIONAL STUDY

Microbial Metabolites and Outcomes of Pregnancy Study

ClinicalTrials.gov

This is a completed observational registry study with no published results reported; it establishes TMAO as a candidate biomarker in pregnancy but provides no outcome data to assess clinical utility.

PreliminaryHypertensive Disorder of Pregnancy NCT06362356 The Cleveland Clinic

Reported

Sample size (actual enrollment)201

Primary outcome measure 1TMAO level at 10–14 weeks gestation

Primary outcome measure 2TMAO level at 24–28 weeks gestation