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Mohamed Elshaer

Ain Shams University

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SEP 9, 2026 · JOURNAL ARTICLE

Lurasidone ameliorates doxorubicin-induced chemobrain in male Wistar rats: involvement of the hippocampal and prefrontal cortex CREB/BDNF/Glt-1 axis and glutamate homeostasis

Frontiers in Pharmacology

First-in-vivo evidence from a single small animal study without clinical validation, demonstrating mechanism but requiring confirmation in larger preclinical and human studies before clinical application.

PreliminaryIntensive Care Unit Cognitive Disorders Sherif A. Kamar Esraa M. Elnahas

Study details

Participantsn = 48

DesignPreclinical controlled animal experiment

InterventionLurasidone co-treatment in doxorubicin-expo…

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