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Researcher

Naima S. Dahir

University of Michigan

1 development in the corpus

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SEP 3, 2026 · JOURNAL ARTICLE

Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced weight gain in female mice

Nature Communications

Mechanistic study in a mouse model proposing a novel signaling pathway for clozapine-induced weight gain, without evidence of clinical translation or validation in humans.

Hypothesis-GeneratingBaijie Xu Luis E. Gimenez Neurotransmitter Receptor Influence on Behavior

Study details

DesignExperimental animal model study with geneti…

InterventionClozapine administration; genetic deletion…

ComparatorVehicle or wild-type control; antipsychotic…

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