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Mengru Tian

Henan Tianguan Group (China)

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SEP 11, 2026 · JOURNAL ARTICLE

Esomeprazole inhibits EGF-induced invasion and migration of gastric cancer cells

Peerj

In vitro mechanistic study demonstrating that esomeprazole modulates a signaling pathway implicated in gastric cancer cell invasion; raises a question about therapeutic potential rather than answering one in a clinical or animal model.

Hypothesis-GeneratingXuanruo Zhang Zisen Zhang Pi3k/akt/mtor Signaling in Cancer

Study details

DesignIn vitro cell line study

InterventionEsomeprazole, with or without EGF stimulati…

ComparatorEGF-stimulated untreated cells; afatinib al…

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