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Guoxu Zhang

Command Hospital

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SEP 10, 2026 · JOURNAL ARTICLE

Systematic adolescent-centered supportive care program is associated with improved psychological status, treatment adherence, and social adaptation in adolescents with thyroid cancer undergoing radioiodine-131 therapy: a retrospective before-after cohort study with historical controls

Frontiers in Endocrinology

A retrospective before-after cohort study with historical controls showing clinically meaningful improvements in anxiety, depression, adherence, and social outcomes in adolescents with thyroid cancer, but requiring prospective RCT confirmation to establish causality.

PromisingGuoxiu Lu Qiwen Zhong Thyroid Cancer Diagnosis and Treatment

Reported

Sample size220

Observation group n135

Control group n85

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