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Panteleimon E. Papakonstantinou

Mater Private Hospital

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JUL 11, 2026 · JOURNAL ARTICLE

Safety and efficacy of DOACs in clinically complex phenotypes of patients with atrial fibrillation: focus on frailty, multimorbidity and polypharmacy

Expert Opinion on Drug Safety

A narrative review synthesizing evidence on DOAC safety and efficacy in complex AF phenotypes, offering expert recommendations for individualized care rather than reporting a single original empirical result.

Expert GuidanceHeart Failure Treatment and Management Gregory Y.H. Lip Panteleimon E. Papakonstantinou

Study details

DesignNarrative review

InterventionDirect oral anticoagulants (DOACs)

ComparatorVitamin K antagonists (warfarin) and other…

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