Researcher

Fei Wang

Department of Epidemiology and Health Statistics, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Hebei, Shijiazhuang, China.

2 developments in the corpus

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AUG 14, 2026 · JOURNAL ARTICLE

Metformin modulates the phenotypes of tumor-associated macrophages in glioblastoma in a context-dependent manner by promoting the homeostasis of macrophages

Frontiers in Oncology

Preclinical syngeneic mouse model study with mechanistic in vitro work showing metformin + radiotherapy prolongs survival and reduces tumor burden through immune reprogramming, but lacks human data and hard clinical endpoints.

PromisingBingjie Guan Metabolism, Diabetes, and Cancer Benhua Xu

Reported

Survival prolongationsignificantly prolonged

Tumor burdenreduced

CD8+/Treg ratioelevated

AUG 6, 2026 · JOURNAL ARTICLE

Association of air pollutant levels and blood pressure variability in patients with essential hypertension: a distributed lag analysis study.

Blood Pressure

Observational study with adequate sample size demonstrating associations between multiple air pollutants and blood pressure variability in hypertensive patients, but lacks a comparator group and causal design.

PromisingLongmei Tang Yatian Liu Hypertension

Reported

Sample size1658

PM2.5 effect on dSBPSD (10-μg/m³…1.08 (95% CI: 0.15, 2.02)

PM2.5 effect on dSBPCV (10-μg/m³…0.80 (95% CI: 0.11, 1.50)