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Linzi Song

Fudan University

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AUG 14, 2026 · JOURNAL ARTICLE

CD39-associated myeloid-T-cell coordination within an immunoregulatory neighborhood linked to treatment resistance in triple-negative breast cancer

Breast Cancer Research

Comprehensive multi-omics analysis identifying CD39-associated immunoregulatory mechanisms linked to immunotherapy resistance in TNBC, with independent validation and prognostic association, but lacking prospective clinical trial data or intervention outcomes.

PromisingCheng Jin Tryptophan and Brain Disorders Guoguo Shang

Reported

Sample size (scRNA-seq cohort)156120

Number of tumor and metastatic sa…27

Number of patients with TNBC (scR…14

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