Massachusetts General Hospital

SEP 11, 2026 · PHASE 4 TRIAL

The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression

ClinicalTrials.gov

This is a Phase 4 trial registration with no posted results; the study is actively recruiting and designed to explore lumateperone's effects on mood, inflammation, and brain aging in bipolar depression.

SEP 10, 2026 · INTERVENTIONAL STUDY

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

ClinicalTrials.gov

This is a recruiting interventional study testing feasibility and acceptability of a behavioral intervention for PrEP adherence in pregnant women; no results are yet reported in this registry record.

SEP 9, 2026 · INTERVENTIONAL STUDY

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

ClinicalTrials.gov

This is a completed registry record with no posted results; the study enrolled 126 participants in an interventional design testing transcutaneous vagus nerve stimulation against sham, but outcome data are not reported in this source.

SEP 9, 2026 · INTERVENTIONAL STUDY

Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals

ClinicalTrials.gov

This is a terminated pilot study with only 3 enrolled participants, designed to assess feasibility and acceptability of an adapted smoking cessation intervention; no efficacy results are reported in this registry record.

AUG 19, 2026 · INTERVENTIONAL STUDY

Mindfulness-based Cognitive Therapy for the Chronic Pain-depression Co-morbidity Among Older Black Adults in the Community; The Quiet Focus Open Pilot

ClinicalTrials.gov

This is an open pilot feasibility study with 12 participants and no reported results; it is designed to inform a future RCT and does not yet provide efficacy data.

AUG 13, 2026 · PHASE 4 TRIAL

Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)

ClinicalTrials.gov

This is a Phase 4 registry record with planned enrollment of 65 participants and no reported results; it describes an active interventional trial measuring peak VO2 as a surrogate endpoint, but outcomes have not yet been posted.

AUG 13, 2026 · INTERVENTIONAL STUDY

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

ClinicalTrials.gov

This is a completed registry record with no posted results; it describes a planned interventional study using surrogate neurophysiological endpoints (fMRI brain activity, heart rate variability) in a small sample, which constitutes early-phase evidence pending outcome publication.

AUG 13, 2026 · OBSERVATIONAL STUDY

WeighT LOSS Surgery and Comprehensive Cardiometabolic Responses to to EXercise

ClinicalTrials.gov

This is a completed observational registry study with small enrollment (n=21) examining cardiometabolic responses to exercise after bariatric surgery; results are not yet reported in this registry record.