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Xuena Chen

Shandong University

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AUG 14, 2026 · JOURNAL ARTICLE

Programmable ZBTB7A RNA N6-methyladenosine site-specific demethylation suppresses colorectal cancer liver metastasis

Molecular Cancer

Mechanistic study identifying a putative therapeutic target (m6A site-specific demethylation of ZBTB7A) in colorectal cancer metastasis using multi-omics and cell-based assays, but lacking in vivo efficacy data or clinical validation.

Hypothesis-GeneratingHuili Hu Huanlu Qiu Epigenetics and DNA Methylation

Study details

InterventionTargeted RNA m6A erasure (TRME) system achi…

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