SEP 10, 2026 · JOURNAL ARTICLE
Adipocyte Gata3 Is a Diet-Inducible Driver of Pathological Adipose Remodeling and Systemic Metabolic Disease
Cells
Mechanistic and functional genomics study in animal models identifying a transcriptional regulator and proposing a causal pathway; lacks clinical outcome data and human validation beyond re-expression experiments.
Study details
DesignTransgenic mouse study with adipocyte-speci…
InterventionAdipocyte-specific Gata3 deletion; human GA…
ComparatorWild-type or control mice on high-fat diet