DNA and Nucleic Acid Chemistry

SEP 8, 2026 · JOURNAL ARTICLE

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Molecular Medicine Reports

This is a narrative review synthesizing preclinical and early-stage research on aptamers for colorectal cancer, raising opportunities rather than reporting primary trial evidence or definitive clinical results.

SEP 7, 2026 · JOURNAL ARTICLE

Aptamer-Functionalized Liposomes for Targeted Delivery of Anticancer Drugs in Lung Cancer

Molecules

Early-phase in vitro characterization of a novel drug delivery system in cell lines; demonstrates proof-of-concept but lacks in vivo validation, clinical endpoints, or comparison to standard therapies.

AUG 17, 2026 · JOURNAL ARTICLE

Potentiating In Vivo Precision Cancer Therapy With Modularized Aptamer‐Chemotherapeutics Conjugates Based on DNA Tiling‐Mediated Structural Nanotechnology

Small

Early-stage preclinical work demonstrating proof-of-concept for a novel DNA nanostructure in a single mouse tumor model, lacking controlled comparators, toxicity data, and mechanistic validation needed for clinical translation.

AUG 9, 2026 · JOURNAL ARTICLE

A Light-ControlledDNA Nanoclaw Machine: IntegratedMultiplexed Recognition, Spatiotemporally Programmable Therapy, andReal-Time Electrochemical Signaling for Precision Receptor Regulation

Analytical Chemistry

This is an early-stage proof-of-concept study of a novel nanodevice design using in vitro cell culture; it demonstrates feasibility and mechanism but provides no clinical efficacy data, animal studies, or comparison to existing therapeutics.