AUG 17, 2026 · JOURNAL ARTICLE
Potentiating In Vivo Precision Cancer Therapy With Modularized Aptamer‐Chemotherapeutics Conjugates Based on DNA Tiling‐Mediated Structural Nanotechnology
Small
Early-stage preclinical work demonstrating proof-of-concept for a novel DNA nanostructure in a single mouse tumor model, lacking controlled comparators, toxicity data, and mechanistic validation needed for clinical translation.
Reported
Tube circumference118.6 nm
Tube length478 nm
Assembly efficiencyalmost up to 90%