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Mon S Bryant

Pulmonary Section, Medical Care Line, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA; Division of Endocrinology, Diabetes, and Metabolism, Baylor College of Medicine, Houston, TX, USA.

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JUL 1, 2027 · JOURNAL ARTICLE

Metformin added to lifestyle intervention for physical function in older adults with obesity (DEMFOS trial): a randomised controlled trial.

The Lancet. Healthy Longevity

Randomised placebo-controlled trial showing intensive lifestyle intervention improves physical function in older adults with obesity, but metformin adds no benefit beyond placebo.

Strong EvidenceViola Viola Mon S Bryant Marlene Aguilar

Reported

Primary endpointChange in modified physical performance tes…

Sample size114

Mean difference (intensive lifest…0·1 points

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