Head and Neck Cancer Studies

SEP 7, 2026 · JOURNAL ARTICLE

Do not try this at home: patterns and outcomes of radiation dose de-escalation in p16-positive oropharyngeal carcinoma

Frontiers in Oncology

Large national cohort study with hard clinical outcome (overall survival) showing inferior outcomes with dose de-escalation, aligning with recent randomized evidence and supporting current standard-of-care dosing.

SEP 6, 2026 · JOURNAL ARTICLE

Prophylactic treatment of regional lymph drainage zones in stage T1–2N0M0 oral cavity cancer: a retrospective population-based analysis

South Russian Journal of Cancer

Rigorous population-based retrospective cohort study with multivariable adjustment comparing four treatment strategies in localized oral cavity cancer, demonstrating significantly improved survival with elective neck dissection versus omission or radiotherapy alone.

SEP 4, 2026 · JOURNAL ARTICLE

The road ahead: understanding recurrence and prognostic factors in oral cavity cancer

Reports of Practical Oncology & Radiotherapy

Single-institution prospective cohort with uniform treatment identifying prognostic factors for disease-free survival in oral cavity cancer, but lacks a comparator group and generalizability is limited to one centre.

SEP 4, 2026 · JOURNAL ARTICLE

Semi-occluded vocal tract exercises improvement in patients after laryngeal and hypopharyngeal cancer treatment

Russian Bulletin of Otorhinolaryngology

A small randomized controlled trial with a statistically significant primary endpoint (p=0.0008) and reported improvements in swallowing, voice, and GRBAS scores, but limited by modest sample size, lack of reported effect sizes, and insufficient detail on methods and follow-up.

SEP 4, 2026 · JOURNAL ARTICLE

Associations of baseline [18F]FDG PET/CT metabolic parameters with the efficacy of neoadjuvant immunotherapy plus concurrent chemoradiotherapy in patients with locally advanced gastric adenocarcinoma: a post hoc analysis of the Neo-PLANET phase II trial

BMC Medical Imaging

Post hoc analysis of a phase II trial with small sample (n=29) and surrogate/exploratory endpoints; findings are hypothesis-generating and require validation in larger populations.

SEP 4, 2026 · JOURNAL ARTICLE

Neoadjuvant combined immunotherapy with intratumoral TransCon TLR7/8 Agonist and systemic TransCon IL-2 β/y or pembrolizumab in patients with locally advanced oral cancer—a monocentric experience

Cancer Immunology Immunotherapy

Single-center cohort of six patients from a prematurely terminated phase 2 trial with descriptive analysis only; feasibility and immune remodeling demonstrated but efficacy and safety conclusions explicitly limited by sample size and trial discontinuation.

SEP 4, 2026 · JOURNAL ARTICLE

An open-label randomised controlled trial protocol evaluating a Siddha add-on regimen for radiotherapy induced oral mucositis in head and neck cancer patients

Frontiers in Medicine

This is a protocol paper for an ongoing Phase II trial with no results reported; it describes planned methodology and endpoints only, representing preliminary evidence generation in progress.

AUG 28, 2026 · JOURNAL ARTICLE

Veil-Based Collector Device Enabling Self-Collected Cervicovaginal Sampling for Site-of-Care Primary HPV-Based Cervical Cancer and Sexually Transmitted Infections Screening: A Pilot Feasibility Study in Romania

Diagnostics

Single-centre pilot feasibility study with uncontrolled design and surrogate endpoints (molecular detection); demonstrates technical capability and epidemiological associations but lacks comparative evidence or clinical outcome data needed to guide practice.