Loading

PeerCurrent.com|Stay current with the people and research shaping what comes next.

About Privacy Terms Support

PeerCurrent

PcPeerCurrent

Your Feed AI Summary Saved Board Expert Discussion This Week in Your Field

Follows Journals Trials Guidelines Markets

Set your cadence Alerts Settings Help

Back to follows

Researcher

Xin-De Chen

1 development in the corpus

Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.

For You Latest Breakthroughs Trials Reviews Guidelines

Latest

Everything in the corpus, newest first.

SEP 7, 2026 · JOURNAL ARTICLE

Glucose-induced histone lactylation confers metformin resistance in colorectal cancer stem cells

Nature Communications

A mechanistic study identifying a metabolic pathway and proposing drug targets, but without clinical efficacy data, human trials, or validation of the proposed combination therapy.

Hypothesis-GeneratingMetabolism, Diabetes, and Cancer Xiang-Rui Li Li Deng

Reported

Primary observationHigh glucose promotes metformin resistance…

Mechanism: histone lactylation si…H3K18la

Pharmacological targets identifiedLDHA and CD36

PeerCurrent.com|Stay current with the people and research shaping what comes next.

About Privacy Terms Support