JUL 20, 2026 · JOURNAL ARTICLE
The relative immunogenicity of 20-valent and 15-valent pneumococcal conjugate vaccines: A systematic review and network meta-analysis.
Human Vaccines & Immunotherapeutics
Network meta-analysis of 17 trials confirms differential serotype-specific immunogenicity between higher-valent pneumococcal vaccines, with PCV15 showing mostly superior responses.
Reported
Primary endpointOPA geometric mean titers at 30 days
Trials meeting inclusion17 trials
Trials contributing OPA data9 trials