SEP 4, 2026 · JOURNAL ARTICLE
Fasting by the Clock: A Randomized Comparison of 12:12, 14:10 and 16:8 Time-Restricted Eating for Weight and Metabolic Outcomes in Adults With Overweight or Obesity
Journal of Medicine Pharmacology and Medical Devises Technology
Well-designed three-arm RCT with adequate sample size, clear primary endpoints (weight loss and metabolic markers), and clinically meaningful effect sizes across all groups, though single-centre and short-term follow-up limit generalizability.
Reported
Mean percentage weight loss (12:1…3.9±1.8%
Mean percentage weight loss (14:1…6.1±2.1%
Mean percentage weight loss (16:8…7.5±2.3%