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Julia Lopatnikova

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AUG 11, 2026 · JOURNAL ARTICLE

Multimodal profiling of HER2/neu-specific TCR-T cells reveals clonotype-dependent activation programs underlying differential cytotoxic efficacy

Communications Biology

Single-centre mechanistic study of three TCR constructs using multimodal profiling with in vivo tumour modelling; identifies functional hierarchy but lacks comparative efficacy statistics, power calculation, or clinical translation.

PreliminaryOlga Perik-Zavodskaia CAR-T Cell Therapy Research Vaccines and Immunoinformatics Approaches

Reported

TCR constructs analysed3

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