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A. DeMichele

University of Pennsylvania

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AUG 7, 2026 · JOURNAL ARTICLE

HER2DX in early-stage HER2-positive breast cancer: a review of clinical utility

ESMO Open

Meta-analyses demonstrate independent prognostic and predictive associations of HER2DX scores with survival and pathological response beyond standard factors, supported by translational validation and prospective trial data.

Strong EvidenceNadine Tung Breast Cancer Treatment Studies A.C. Wolff

Study details

DesignNarrative review synthesizing meta-analyses…

InterventionHER2DX genomic-clinical test generating pro…

ComparatorStandard clinicopathological assessment (tu…

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