AUG 14, 2026 · JOURNAL ARTICLE
Single-cell and spatial transcriptomics define the LAMC2+ malignant subtype orchestrating vasculogenic mimicry-mediated resistance in head and neck cancer
npj Precision Oncology
Mechanistic study using transcriptomics and experimental models to propose a resistance pathway; lacks clinical trial evidence or outcome validation of the proposed therapeutic strategy.
Study details
DesignMechanistic translational study integrating…
InterventionFunctional characterization of LAMC2; TGF-β…
ComparatorLAMC2-low or other malignant subtypes; sing…