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Choong‐kun Lee

Yonsei University

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AUG 7, 2026 · JOURNAL ARTICLE

Spatial organisation of tumor-infiltrating B-cells informs immune checkpoint inhibitor response in Claudin 18.2-expressing gastric cancer

Clinical Cancer Research

Prospective profiling study identifying spatial B-cell organization as a potential biomarker for ICI response in CLDN18.2-expressing gastric cancer, with validation across five cohorts including a phase 3 trial, but lacking randomized comparison or prospective outcome prediction.

PromisingRaghav Sundar Joseph J. Zhao Choong‐kun Lee

Reported

Sample size (primary cohort)103

Cells profiled (multiplex immunoh…7,423,483

Regions of interest profiled2,315

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