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Zeyao Ye

Chinese Academy of Sciences

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AUG 12, 2026 · JOURNAL ARTICLE

Perioperative PD-1 inhibitor plus chemotherapy versus chemotherapy alone in gastric cancer with PAN metastasis undergoing D2 gastrectomy and PAND: a single-center retrospective cohort study

Frontiers in Immunology

A single-center retrospective cohort study shows higher pathological response and 3-year OS with PD-1 inhibitor plus chemotherapy versus chemotherapy alone in gastric cancer with para-aortic node metastasis, but lacks randomization, prospective design, and multicenter validation.

PromisingMetastasis and Carcinoma Case Studies Weixing Wu Xiangliu Chen

Reported

Pathological complete response ra…37.1%

Pathological complete response ra…4.2%

P-value for pCR differenceP<0.001

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