Drug or technology

Laser-ablation Synthesis of Nanoparticles

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SEP 8, 2026 · JOURNAL ARTICLE

Low-level laser irradiation stimulated tumoricidal impacts and dose-dependent modulation of Wnt signaling in three-dimensional human colorectal cancer microspheres

Lasers in Medical Science

In vitro mechanistic study in a 3D model system showing dose-dependent effects on colorectal cancer cells, but without clinical outcome data, in vivo validation, or comparison to standard therapies.

PreliminaryHesam Saghaei Bagheri Çıgır Biray Avci Nafiseh Didar Khosrowshahi

Reported

Mean microsphere diameter305.85 ± 19.07 μm

High-dose LLLI fluence80 J/cm²

Low-dose LLLI fluence2 J/cm²

AUG 11, 2026 · JOURNAL ARTICLE

Decoding shape- and type-dependent cellular toxicity of plasmonic nanoparticles in healthy and cancer cells

Nanotoxicology

This is a mechanistic, in vitro comparative study of nanoparticle toxicity across cell types and conditions, offering structure–activity insights but lacking efficacy data, clinical endpoints, or in vivo validation necessary to guide therapeutic development.

Hypothesis-GeneratingMerve Bacanlı Gold and Silver Nanoparticles Synthesis and Applications Hakan Erdoğan

Reported

Wavelength of laser activation808 nm

Nanoparticle size tested20 nm