Drug or technology

Sotorasib

2 developments in the corpus

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SEP 11, 2026 · PHASE 3 TRIAL

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

ClinicalTrials.gov

This is an active Phase 3 trial registration with no results posted; the study design and planned endpoints are described but no outcome data are available.

PreliminaryNCT05920356 Amgen Sotorasib

Reported

Planned enrollment750

Primary endpoint 1Progression-free Survival (PFS)

Primary endpoint 2Overall Survival (OS)

SEP 11, 2026 · PHASE 2 TRIAL

A Study of Sotorasib in People With Non-Small Cell Lung Cancer

ClinicalTrials.gov

This is a Phase 2 clinical trial registration with no posted results; it describes a planned study of sotorasib in treatment-naive advanced NSCLC with KRAS G12C mutation, currently recruiting.

PreliminaryNon Small Lung Cancer Sotorasib Memorial Sloan Kettering Cancer Center

Reported

Planned enrollment39

PhasePHASE 2

Primary outcome measureResponse to therapy, within 6 months of the…