AUG 12, 2026 · JOURNAL ARTICLE
Case Report: Synchronous cutaneous and pineal metastases from gastric adenocarcinoma—inter-lesion biomarker heterogeneity and multi-line targeted therapy
Frontiers in Oncology
A single case report describing an extraordinarily rare metastatic pattern with anecdotal treatment response; raises questions about multi-site biomarker heterogeneity and sequential targeted therapy but provides no controlled evidence or generalizable outcomes.
Reported
Patient age43 years
Proportion of intracranial tumors…less than 1%