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Shenggen Zhu

Xinyu University

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AUG 17, 2026 · JOURNAL ARTICLE

Exercise as a multimodal intervention for adolescent depression: integrating neuroplasticity, BDNF signaling, stress biomarkers, exercise intensity, digital mental health interventions, and precision psychiatry

Frontiers in Psychiatry

A narrative review synthesizing evidence on exercise for adolescent depression that acknowledges heterogeneity, limited mechanistic proof, and the need for future research—informative for clinical context but not a definitive evidence synthesis or meta-analysis.

Expert GuidanceTryptophan and Brain Disorders Jun Ou 何吉桥

Study details

DesignNarrative review

InterventionPhysical exercise, particularly moderate-to…

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