Drug or technology

Lipid Nanoparticles

2 developments in the corpus

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AUG 16, 2026 · JOURNAL ARTICLE

Delivering the blueprint: Advances and challenges in mRNA therapeutics for the respiratory system.

International Journal of Pharmaceutics: X

This is a systematic review article synthesizing mechanisms, delivery methods, challenges, and safety considerations for mRNA-LNP therapeutics in pulmonary disorders, providing expert assessment of the field rather than reporting original trial data.

Expert GuidanceFangru Jia Respiratory Diseases Mrna Therapeutics

Reported

Delivery efficiency to ATII cells…approximately 30%

Lung selectivity of second-genera…∼95%

Ionizable lipid pKa range for air…6.2–6.8

AUG 12, 2026 · JOURNAL ARTICLE

Targeted delivery of mRNA to immune cells for in vivo cell therapy.

Drug Delivery

A comprehensive review article synthesizing current knowledge on mRNA delivery engineering strategies to immune cells, identifying translational barriers and technical advances rather than reporting original experimental results or clinical outcomes.

Expert GuidanceNanoparticles Jinfeng Deng Yumin Li

Reported

Ex vivo CAR-T manufacturing durat…typically 3–4 weeks