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Peripheral Nerve Disorders

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AUG 10, 2026 · JOURNAL ARTICLE

Tirzepatide Use Is Associated with Reduced Risk of Carpal Tunnel Syndrome in Overweight and Obese Adults

Clinical Pharmacology & Therapeutics

Retrospective cohort study with propensity score matching showing reduced CTS risk with tirzepatide versus comparators, but observational design, potential residual confounding, and surrogate clinical outcomes limit strength.

PromisingShuo‐Yan Gau Peripheral Nerve Disorders Diagnosis and Treatment of Venous Diseases

Reported

Hazard ratio (tirzepatide vs GLP-…0.82

95% CI (tirzepatide vs GLP-1RA) f…0.71–0.95

Hazard ratio (tirzepatide vs othe…0.75

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