AUG 26, 2026 · JOURNAL ARTICLE
Personalised Nutraceutical Treatment Guided by MTHFR Genotype in Mental Health: A Retrospective Cohort Study
Nutrients
Retrospective cohort study without control group in a single integrative practice clinic; shows feasibility and safety but lacks comparison arm and rigorous design needed to establish efficacy of genotype-guided nutraceutical treatment.
Reported
Primary endpoint: K10 score changemean decrease of 4 points
Clinical improvement rate72%
Sample size50