Researcher

Shion Kachi

Japan Cancer Society

2 developments in the corpus

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AUG 10, 2026 · JOURNAL ARTICLE

Association of Urinary pH With Overall Survival in Patients With Stage IV Cancer: A Single‐Center Retrospective Cohort Study

Cancer Nexus

Single-center retrospective cohort with no concurrent control group, studying an association between urinary pH and survival in stage IV cancer patients; the authors explicitly state findings are associative and hypothesis-generating rather than causal, and call for prospective studies.

PreliminaryHiromi Wada Ryoko Narui Hiromasa Morikawa

Reported

5-year overall survival39.8%

10-year overall survival28.8%

1-year survival rate, pH ≤5.531.2%

AUG 7, 2026 · JOURNAL ARTICLE

Association of alkalization therapy with long-term survival in stage IV or recurrent colorectal cancer: interaction with RAS mutation status

Frontiers in Oncology

Retrospective single-center cohort without randomization or control group; shows association between urinary pH and survival in RAS-mutant colorectal cancer but cannot establish causation or compare to standard care.

PreliminaryHiromi Wada Hiromasa Morikawa Shion Kachi

Reported

5-year OS rate, overall cohort0.212

95% CI, 5-year OS overall0.113–0.362

Hazard ratio, urinary pH × RAS in…0.22