Center of Excellence in Precision Medicine and Digital Health, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
2 developments in the corpus
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A scoping review synthesizing preclinical and mechanistic evidence on Sp1 in OSCC with scRNA-seq analysis, raising translational questions but reporting no clinical trials or human efficacy data.
This is a systematic review of 33 observational and experimental studies with no randomized controlled trials or clinical outcome data, synthesizing preclinical and correlative evidence that MTDH is overexpressed in HNC and promotes oncogenic functions, but lacking direct evidence of clinical benefit from MTDH-directed intervention.