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Theodora Kougioumtzoglou

University of Patras

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JUL 30, 2026 · JOURNAL ARTICLE

Anticholinergic Burden and Cognitive Function, Depressive Symptoms, and Functional Performance in Individuals With Neurocognitive Disorders: Real-World Evidence

Journal of Integrative Neuroscience

Observational study in real-world clinical setting demonstrates consistent associations between anticholinergic burden and multiple cognitive, functional, and mood domains across diagnostic groups, but cannot establish causation and lacks a comparator intervention.

PromisingMaria Skondra Intensive Care Unit Cognitive Disorders Leonidas Papadopoulos

Reported

Sample size - no cognitive impair…301

Sample size - mild neurocognitive…264

Sample size - Alzheimer's major n…114

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