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Abhisheak Sharma

Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA.

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AUG 17, 2026 · JOURNAL ARTICLE

Simultaneous quantification of seventeen kratom alkaloids and metabolites in human plasma and its application to clinical pharmacokinetic sample analysis.

Pharmaceutical Biology

This is a bioanalytical method development and validation study applied to a small clinical pharmacokinetic sample from regular kratom users, providing first systematic multiplex quantification but lacking efficacy or safety endpoints.

PreliminaryManoj Gundeti Siva Rama Raju Kanumuri Abhisheak Sharma

Reported

Linearity range1–250 ng/mL

Time to peak plasma concentration…1–2 h

Number of alkaloids quantified12

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