SEP 8, 2026 · JOURNAL ARTICLE
Low-level laser irradiation stimulated tumoricidal impacts and dose-dependent modulation of Wnt signaling in three-dimensional human colorectal cancer microspheres
Lasers in Medical Science
In vitro mechanistic study in a 3D model system showing dose-dependent effects on colorectal cancer cells, but without clinical outcome data, in vivo validation, or comparison to standard therapies.
Reported
Mean microsphere diameter305.85 ± 19.07 μm
High-dose LLLI fluence80 J/cm²
Low-dose LLLI fluence2 J/cm²