AUG 12, 2026 · JOURNAL ARTICLE
Comparative Effectiveness of Benzydamine and Salt–Soda–Bicarbonate Mouthwashes versus Routine Care on Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiotherapy
Indian Journal of Medical and Paediatric Oncology
A small quasi-experimental trial with non-random allocation showing salt–soda–bicarbonate mouthwash superior to routine care and benzydamine for oral mucositis reduction over 5 days, but limited by design, sample size, short follow-up, and lack of blinding.
Reported
Sample size per group20
Mean difference: salt–soda–bicarb…0.85
p-value: salt–soda–bicarbonate vs…<0.05