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Keyvan Hejazi

Hakim Sabzevari University

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AUG 12, 2026 · JOURNAL ARTICLE

The effects of combined functional and aerobic training along with folic acid supplementation on serum levels of Isthmin-1, inflammatory markers and insulin resistance in men with obesity

BMC Sports Science Medicine and Rehabilitation

A small double-blind RCT with clear surrogate endpoints (inflammatory markers, insulin resistance, body composition) showing favourable effects of combined training plus folic acid, but limited by small sample size (n=44, 11 per group) and surrogate rather than hard clinical outcomes.

PromisingHassane Zouhal Ayoub Saeidi Keyvan Hejazi

Reported

Sample size44

Sample size per group11

Body weight and BMI reduction (CT…P = 0.001

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