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Researcher

Tiantian Wei

Guangdong Academy of Medical Sciences

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AUG 5, 2026 · JOURNAL ARTICLE

Macrophage-to-myofibroblast transition-derived itaconate promotes bone metastasis in lung cancer through targeting of HSPA8

Experimental & Molecular Medicine

Mechanistic study in animal models of a proposed metabolic axis in lung cancer bone metastasis; no clinical outcome data, human efficacy trials, or direct comparison to standard therapy reported.

Hypothesis-GeneratingZhidan Tan Jinfeng Wang Tiantian Wei

Study details

DesignIntegrated mechanistic profiling (metabolom…

InterventionAdeno-associated virus-delivered PSAT1 shor…

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